SERBP1 Antibody / PAI-RBP1 | V8445SAF-100UG

SERBP1 Antibody / PAI-RBP1 | V8445SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: SERBP1/3494

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, IHC-P

Buffer: N/A

Limitation: This SERBP1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: SERBP1 is a membrane-associated protein that localizes to the nucleus, the perinuclear region of the cytoplasm and the plasma membrane. It is believed to play a role in the regulation of mRNA stability, as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition, SERBP1 interacts with Mi2-s antiapoptotic action in ovarian cell types. SERBP1 is overexpressed in ovarian cancer, suggesting a possible role in tumorigenesis and tumor metastasis.

Immunogen: A portion of amino acids 3-139 from the human protein was used as the immunogen for the SERBP1 antibody.

Storage: Store the SERBP1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).