SENP6 Core Domain, His-tag | 81097

SENP6 Core Domain, His-tag | 81097 | Gentaur US, UK & Europe Disrtribition

Category: Ubiquitination/Deubiquitylating Enzymes

Application: This enzyme is active in the SUMO3-CHOP assay.

Background: SENP6 is a SUMO/sentrin specific protease that functions to remove SUMO from conjugated proteins. SENP6 has been shown to deSUMOylate a member of the ligand-activated transcription factores called retinoid X receptor alpha. The transcriptional activity of RXRalpha is regulated by SUMOylation. Researchers have demonstrated that SENP6 has a preference for SUMO2/3 conjugates over SUMO1 conjugates.

Description: Human SENP6 Core Domain recombinant protein, with His-tag, expressed in E. coli.

Product Type: Protein

Shippement Condition: -80°C (dry ice)