Description
Semaphorin-4D Antibody / SEMA4D | V2453-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: SEMA4D/933
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: FACS, IF
Buffer: N/A
Limitation: This Semaphorin-4D antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
Immunogen: Human recombinant protein was used as the immunogen for the Semaphorin-4D antibody.
Storage: Store the Semaphorin-4D antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
