Description
SDHB Polyclonal Antibody | E-AB-40481 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC
Research Area: Cancer, Cell Biology, Metabolism, Signal Transduction
Background: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Lead Time: Order now, ship in 3 day
Concentration: 1mg/mL
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Immunogen: Recombinant Human Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial protein
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification: Antigen Affinity Purification
Dilution: WB 1:20000-1:100000 IHC 1:100-1:400
Conjugation: N/A
Calculated Molecular Weight: 31 kDa
Observed Molecular Weight: 31 kDa
Clonality: Polyclonal
