SARS-CoV GD01 Spike Trimer Protein (R667A, KV968-969PP), His Tag (MALS verified) | SPN-S52Ht-500ug

SARS-CoV GD01 Spike Trimer Protein (R667A, KV968-969PP), His Tag (MALS verified) | SPN-S52Ht-500ug| Gentaur Distribution US, UK & Europe

It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Source: SARS-CoV GD01 Spike Trimer, His Tag (SPN-S52Ht) is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. It contains AA Ser 14 - Pro 1195 (Accession # AAP51227.1 (R667A, KV968-969PP) ).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Ser 14 - Pro 1195.

Conjugate: Unconjugated.

Molecular Weight: 136.5 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 136.5 kDa. The protein migrates as 160-190 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS.

Storage Conditions: -20℃.

Shipping Conditions: RT