Description
SARS-CoV-2 Variants Neutralizing Antibody 6-plex Panel (Flow Cytometry Multiplex Bead Assay) | FCM-N04R| Gentaur Distribution US, UK & Europe
Since December 2019, the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated disease, COVID-19, has caused a devastating pandemic worldwide.As the virus spreads globally, the continuous emergence of new mutant strains escalated the challenge on humans.To facilitate the mutant-related research, drug trials and vaccine development, a multiplex serological test for assessing antibody responses to mutant strains is in urgent need.
Source: Since December 2019, the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated disease, COVID-19, has caused a devastating pandemic worldwide.As the virus spreads globally, the continuous emergence of new mutant strains escalated the challenge on humans.To facilitate the mutant-related research, drug trials and vaccine development, a multiplex serological test for assessing antibody responses to mutant strains is in urgent need.
Molecule: Spike RBD.
Format: Solid.
Species: SARSN/ACoVN/A2.
Application: The kit is developed for qualitative detection of Anti-SARS-CoV-2 Variants (Alpha, Beta, Gamma, Delta, Omicron) neutralizing antibody in human serum.
Kit Component: SARS-CoV-2 Variants Neutralizing Antibody 6-plex Panel is a multiplex bead-based competitive immunofluorescence assay, utilizing flow cytometry for data acquisition and classification. Six SARS-CoV-2 Spike protein (WT / Alpha / Beta / Gamma / Delta / Omicron ) were conjugated to 6 fluorochrome-encoded microspheres respectively. Anti-SARS-CoV-2 neutralizing antibody in blood specimens competes with ACE2, for binding to Spike protein encapsulated 6-plex beads. Streptavidin conjugated R-phycoerythrin (SA-PE) was employed to detect biotinylated ACE2 bound to the beads. The intensity of PE fluorescence was assessed by flow cytometry at wavelength of 575 nm approximately, in inversely proportion to the Anti-SARS-CoV-2 neutralizing antibody in blood specimens. The intensity of APC fluorescence was applied to classify bead populations, at wavelength of 670 nm approximately.
Stability: 1. Unopened kit should be stored at 2℃-8℃ upon receiving. 2. Find the expiration date on the outside packaging and do not use reagents past their expiration date. 3. The opened kit should be stored per components table. The shelf life is 87 days from the date of opening.
Storage Conditions: 2-8℃.
Shipping Conditions: Blue ice
