SARS-CoV-2 Spike RBD Protein (S477N, E484K), His Tag (MALS verified) | SPD-C52Hq-1mg

SARS-CoV-2 Spike RBD Protein (S477N, E484K), His Tag (MALS verified) | SPD-C52Hq-1mg| Gentaur Distribution US, UK & Europe

It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Source: SARS-CoV-2 Spike RBD (S477N, E484K), His Tag (SPD-C52Hq) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (S477N, E484K) ). The mutations (S477N, E484K) were identified in the SARS-CoV-2 variant B.1.620, which was found to circulate in Europe and Central Africa.

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Arg 319 - Lys 537.

Conjugate: Unconjugated.

Molecular Weight: 26.5 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.5 kDa. The protein migrates as 32-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT