Description
SARS-CoV-2 Spike RBD Protein (L452R, T478K, N501Y), His Tag (MALS verified) | SPD-C5225-100ug| Gentaur Distribution US, UK & Europe
It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Source: SARS-CoV-2 Spike RBD (L452R, T478K, N501Y), His Tag (SPD-C5225) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (L452R, T478K, N501Y) ). The mutations (L452R, T478K, N501Y) were identified in the SARS-CoV-2 variants which emerged in Vietnam.
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Arg 319 - Lys 537.
Conjugate: Unconjugated.
Molecular Weight: 26.6 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.6 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
