SARS-CoV-2 Spike NTD Protein (T19R, G142D, EF156-157del, R158G), His Tag (MALS verified) | S1D-C52Hh-100ug

SARS-CoV-2 Spike NTD Protein (T19R, G142D, EF156-157del, R158G), His Tag (MALS verified) | S1D-C52Hh-100ug| Gentaur Distribution US, UK & Europe

It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Source: SARS-CoV-2 Spike NTD, His Tag (S1D-C52Hh) is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (Accession # QHD43416.1). The mutations (T19R, G142D, EF156-157del, R158G) were identified in the SARS-CoV-2 Delta variant (Pango lineage: B.1.617.2; GISAID clade: GK; Nextstrain clade: 21A/21I/21J).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Ser 13 - Leu 303.

Conjugate: Unconjugated.

Molecular Weight: 34.6 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.6 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT