SARS-CoV-2 Spike NTD Protein, His Tag (BA.4 & BA.5/Omicron) (MALS verified) | SPD-C5246-1mg

SARS-CoV-2 Spike NTD Protein, His Tag (BA.4 & BA.5/Omicron) (MALS verified) | SPD-C5246-1mg| Gentaur Distribution US, UK & Europe

It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Source: SARS-CoV-2 Spike NTD Protein, His Tag (BA.4 & BA.5/Omicron) (SPD-C5246) is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (Accession # QHD43416.1 (T19I, LPP24-26del, A27S, HV69-70del, G142D, V213G) ). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.4 and BA.5).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Ser 13 - Leu 303.

Conjugate: Unconjugated.

Molecular Weight: 34.4 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.4 kDa. The protein migrates as 50-63 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT