Description
SARS-CoV-2 Spike NTD Protein (C136F, Y144del, R190S, D215G, LA242-243del), His Tag (MALS verified) | SPD-C5229-1mg| Gentaur Distribution US, UK & Europe
It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Source: SARS-CoV-2 Spike NTD, His Tag (SPD-C5229) is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (Accession # QHD43416.1). The mutations C136F, Y144del, R190S, D215G, LA242-243del were identified in the SARS-CoV-2 variant C.1.2.
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Ser 13 - Leu 303.
Conjugate: Unconjugated.
Molecular Weight: 34.5 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.5 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
