Description
SARS-CoV-2 S1 protein NTD (L18F, T20N, P26S, D138Y, R190S), His Tag (MALS verified) | S1D-C52He-1mg| Gentaur Distribution US, UK & Europe
It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Source: SARS-CoV-2 S1 protein NTD, His Tag (S1D-C52He) is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (Accession # QHD43416.1). The L18F/ T20N/ P26S/ D138Y/ R190S mutations were identified on the spike protein N-terminal domain (NTD) in the SARS-CoV-2 Gamma variant (Pango lineage: P.1; other names: 20J/501Y.V3).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Ser 13 - Leu 303.
Conjugate: Unconjugated.
Molecular Weight: 34.9 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.9 kDa. The protein migrates as 50-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
