SARS-CoV-2 S1 protein NTD (HV69-70del, Y144del), His Tag (MALS verified) | S1D-C52Hd-100ug

SARS-CoV-2 S1 protein NTD (HV69-70del, Y144del), His Tag (MALS verified) | S1D-C52Hd-100ug| Gentaur Distribution US, UK & Europe

It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Source: SARS-CoV-2 S1 protein NTD (HV69-70del, Y144del), His Tag (S1D-C52Hd) is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (Accession # QHD43416.1 (HV69-70del, Y144del) ). The HV69-70del/Y144del mutations were identified on the spike protein N-terminal domain (NTD) in the SARS-CoV-2 Alpha variant (Pango lineage: B.1.1.7; other names: 20I/501Y.V1 or VOC 202012/01).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Ser 13 - Leu 303.

Conjugate: Unconjugated.

Molecular Weight: 34.5 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.5 kDa. The protein migrates as 50-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT