SARS-CoV-2 S1 protein (HV69-70del, Y144del, N501Y, A570D, D614G, P681H), His Tag | S1N-C52Hr-100ug

SARS-CoV-2 S1 protein (HV69-70del, Y144del, N501Y, A570D, D614G, P681H), His Tag | S1N-C52Hr-100ug| Gentaur Distribution US, UK & Europe

It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Source: SARS-CoV-2 S1 protein, His Tag (S1N-C52Hr) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). HV69-70del, Y144del, N501Y, A570D, D614G, P681H mutations were identified in the SARS-CoV-2 Alpha variant (Pango lineage: B.1.1.7; other names: 20I/501Y.V1 or VOC 202012/01).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Val 16 - Arg 685.

Conjugate: Unconjugated.

Molecular Weight: 76.6 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.6 kDa. The protein migrates as 100-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT