SARS-CoV-2 Nucleocapsid protein, His Tag (BA.4/Omicron) | NUN-C52Hw-100ug

SARS-CoV-2 Nucleocapsid protein, His Tag (BA.4/Omicron) | NUN-C52Hw-100ug| Gentaur Distribution US, UK & Europe

Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

Source: SARS-CoV-2 Nucleocapsid protein, His Tag (BA.4/Omicron) (NUN-C52Hw) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1 (P13L, ERS31-33del, P151S, R203K, G204R, S413R) ). The mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.4; GISAID clade: GRA).

Format: Powder.

Tag: C-6×His.

Expression System: HEK293.

Expression Region: Met 1 - Ala 419.

Conjugate: Unconjugated.

Molecular Weight: 47.1 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.1 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, 0.2M Arginine, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT