Description
SARS-CoV-2 NSP3 Polyclonal Antibody(2019-nCoV) | E-AB-V1039 | Gentaur US, UK & Europe Disrtribition
Category: Polyclonal
Synonyms: Non-structural protein 3,PL2-PRO,Papain-like proteinase,PL-PRO,Replicase polyprotein 1a
Application: ELISA
Reactivity: SARS-COV2
Host: Rabbit
Isotype: IgG
Background: Responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF3. Prevents also host NF-kappa-B signaling.
Lead Time: 7~10 days
Concentration: 0.33mg/ml
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
Dillution: Elisa:1:4000~1:8000
Conjugation: Unconjugated
Immunogen: Recombinant SARS-CoV-2 NSP3(Glu1024-Gln1198)
