Ruxolitinib, Phosphate | 27059-2

Ruxolitinib, Phosphate | 27059-2 | Gentaur US, UK & Europe Disrtribition

Category: Kinase/Kinase Inhibitors

Application: N/A

Background: N/A

Description: Ruxolitinib, also known as INCB18424, is a potent and selective Janus kinase JAK1 and JAK2 inhibitor, with IC50s of 5.9 nM and 5.7 nM, respectively. It inhibited IL-6 and IL-23 effects at concentrations less than 50 nM. Ruxolitinib was effective in the rat adjuvant arthritis model and multiple murine models of arthritis.

Product Type: Inhibitor

Shippement Condition: -20°C