Description
Ruxolitinib, Phosphate | 27059-1 | Gentaur US, UK & Europe Disrtribition
Category: Kinase/Kinase Inhibitors
Application: N/A
Background: N/A
Description: Ruxolitinib, also known as INCB18424, is a potent and selective Janus kinase JAK1 and JAK2 inhibitor, with IC50s of 5.9 nM and 5.7 nM, respectively. It inhibited IL-6 and IL-23 effects at concentrations less than 50 nM. Ruxolitinib was effective in the rat adjuvant arthritis model and multiple murine models of arthritis.
Product Type: Inhibitor
Shippement Condition: -20°C
