Description
RUNX3 Antibody | F44057-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: IHC, IF, WB, ELISA
Buffer: N/A
Limitation: This RUNX3 antibody is available for research use only.
Purity: Antigen affinity
Description: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen: A portion of amino acids 168-197 from the human protein was used as the immunogen for this RUNX3 antibody.
Storage: Aliquot the RUNX3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.