RUNX3 Antibody | F44057-0.4ML

RUNX3 Antibody | F44057-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC, IF, WB, ELISA

Buffer: N/A

Limitation: This RUNX3 antibody is available for research use only.

Purity: Antigen affinity

Description: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen: A portion of amino acids 168-197 from the human protein was used as the immunogen for this RUNX3 antibody.

Storage: Aliquot the RUNX3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.