RUNX2 Polyclonal Antibody | E-AB-30103

RUNX2 Polyclonal Antibody | E-AB-30103 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IF, ELISA

Research Area: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Stem Cells

Background: Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters (By similarity). Inhibits MYST4-dependent transcriptional activation.

Lead Time: 2 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from the Internal region of human RUNX2.

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:500-1:2000, IF 1:50-1:200, ELISA 1:20000

Conjugation: Unconjugated

Calculated Molecular Weight: 57 kDa

Observed Molecular Weight: 56 kDa

Clonality: Polyclonal