Description
RUNX1 Antibody | F53076-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This RUNX1 antibody is available for research use only.
Purity: Antigen affinity
Description: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B- dependent transcriptional activation.
Immunogen: This RUNX1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 421-455 amino acids from the C-terminal region of human RUNX1.
Storage: Aliquot the RUNX1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
