Description
Rubicon Antibody / RUBCN / BARON | F54720-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, FACS, IHC-P, IF
Buffer: N/A
Limitation: This Rubicon antibody is available for research use only.
Purity: Antigen affinity purified
Description: Inhibits PIK3C3 activity; under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation. [UniProt]
Immunogen: A portion of amino acids 241-271 from the human protein was used as the immunogen for the Rubicon antibody.
Storage: Aliquot the Rubicon antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
