RPSA Antibody / 40S Ribosomal protein SA | V8946-20UG

RPSA Antibody / 40S Ribosomal protein SA | V8946-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: rRPSA/6333

Host: Mouse

Clonality: Recombinant Mouse Monoclonal

Isotype: Mouse IgG1, kappa

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 1-2ug/ml

Application Note: Optimal dilution of the recombinant RPSA antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.

Immunogen: Recombinant full-length human RPSA protein was used as the immunogen for the recombinant RPSA antibody.

Storage: Aliquot the recombinant RPSA antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Cell Surface,Cytoplasmic, Nuclear