RPSA Antibody / 40S Ribosomal protein SA | V7301-20UG

RPSA Antibody / 40S Ribosomal protein SA | V7301-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: RPSA/2699

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF, WB, IHC-P

Buffer: N/A

Limitation: This RPSA antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Laminins, a family of extracellular matrix glycoproteins, are the major non-collagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. Reportedly, level of laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype.

Immunogen: Recombinant full length protein was used as the immunogen for the RPSA antibody.

Storage: Store the RPSA antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).