RPA32 Antibody / Replication Protein A2 | V8066SAF-100UG

RPA32 Antibody / Replication Protein A2 | V8066SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: SPM316

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This Replication Protein A2 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Recognizes a protein of 34kDa, identified as a subunit of Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB). RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). It is involved in DNA replication, repair, and recombination. RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase (pol) alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.

Immunogen: A recombinant human full-length protein was used as the immunogen for this Replication Protein A2 antibody.

Storage: Store the Replication Protein A2 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).