RPA2 Polyclonal Antibody | E-AB-60671

RPA2 Polyclonal Antibody | E-AB-60671 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC, IF

Research Area: Cancer, Epigenetics and Nuclear Signaling

Background: Replication protein A 32 kDa subunitis aproteinthat in humans is encoded by theRPA2gene. As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human RPA2 (NP_002937.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 29 kDa/30 kDa/38 kDa

Observed Molecular Weight: 32 kDa

Clonality: N/A