Description
RORC Polyclonal Antibody | E-AB-32827 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Application: WB, ELISA
Research Area: Epigenetics and Nuclear Signaling, Signal Transduction
Background: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.RORC (RAR Related Orphan Receptor C) is a Protein Coding gene. Diseases associated with RORC include Immunodeficiency 42 and Anus Cancer. Among its related pathways are Circadian rythm related genes and Innate Immune System. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and steroid hormone receptor activity. An important paralog of this gene is RORA.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthesized peptide derived from the Internal region of human RORC
Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Dilution: WB 1:500-1:2000, ELISA 1:40000
Conjugation: Unconjugated
Calculated Molecular Weight: 58 kDa
Observed Molecular Weight: 58 kDa
Clonality: Polyclonal
