Description
ROR2, GST-tag | 40296 | Gentaur US, UK & Europe Disrtribition
Category: CAR-T/Protein
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Background: ROR2 is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. ROR2 is selectively expressed in the chondrocytes of all developing cartilage anlagen, where it is essential during initial growth and patterning, as well as subsequently in the proliferating chondrocytes of mature growth plates, where it is required for normal expansion (1). Thus, ROR2 is selectively expressed in and particularly important for the chondrocyte lineage and loss of ROR2 leads to profound skeletal abnormalities (2).
Description: Recombinant human ROR2 (a.a. 427-end), with N-terminal GST-tag, expressed by Sf9 insect cells via a baculovirus expression system.
Product Type: Protein
Shippement Condition: -80°C
