Description
RNF7 Polyclonal Antibody | E-AB-61633 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human
Host: Rabbit
Isotype: IgG
Application: IF
Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism
Background: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human RNF7 (NP_055060.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification: Affinity purification
Dilution: IF 1:20-1:50
Conjugation: Unconjugated
Calculated Molecular Weight: N/A
Observed Molecular Weight: N/A
Clonality: N/A
