RNASE1 Polyclonal Antibody | E-AB-61831

RNASE1 Polyclonal Antibody | E-AB-61831 | Gentaur US, UK & Europe Disrtribition

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Application: WB

Research Area: Epigenetics and Nuclear Signaling

Background: This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2', 3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human RNASE1 (NP_937875.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:500-1:2000

Conjugation: Unconjugated

Calculated Molecular Weight: 17 kDa

Observed Molecular Weight: 15 kDa

Clonality: N/A