RNASE1 Polyclonal Antibody | E-AB-19132

RNASE1 Polyclonal Antibody | E-AB-19132 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC, ELISA

Research Area: Epigenetics and Nuclear Signaling

Background: This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2', 3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

Lead Time: 7~10 days

Concentration: 0.9 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human RNASE1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:100, ELISA 1:5000-1:10000

Conjugation: Unconjugated

Calculated Molecular Weight: 18 kDa

Observed Molecular Weight: Refer to figures

Clonality: Polyclonal