Rhodopsin Antibody (RHO) | F45215-0.08ML

Rhodopsin Antibody (RHO) | F45215-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This RHO antibody is available for research use only.

Purity: Antigen affinity

Description: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.

Immunogen: A portion of amino acids 310-339 from human Rhodopsin was used as the immunogen for this RHO antibody.

Storage: Aliquot the RHO antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.