Rhesus macaque GITR / TNFRSF18 Protein, Fc Tag | GIR-C5255-100ug

Rhesus macaque GITR / TNFRSF18 Protein, Fc Tag | GIR-C5255-100ug| Gentaur Distribution US, UK & Europe

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Source: Rhesus macaque GITR, Fc Tag (GIR-C5255) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Glu 161 (Accession # F7DDV8).

Format: Powder.

Tag: C-Fc.

Expression System: HEK293.

Expression Region: Gln 26 - Glu 161.

Conjugate: Unconjugated.

Molecular Weight: 41.3 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 41.3 kDa. The protein migrates as 48 kDa under reducing (R) condition, and 85 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: Tris with Glycine,  Arginine and NaCl,  pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT