Rhesus macaque / Cynomolgus Complement Factor D / CFD Protein, His Tag (active enzyme) | CFD-R52H3-1mg

Rhesus macaque / Cynomolgus Complement Factor D / CFD Protein, His Tag (active enzyme) | CFD-R52H3-1mg| Gentaur Distribution US, UK & Europe

Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease.

Source: Rhesus macaque / Cynomolgus Complement Factor D, His Tag (CFD-R52H3) is expressed from human 293 cells (HEK293). It contains AA Ile 26 - Ala 253 (Accession # H9EXC1-1). In the region Ile 26 - Ala 253, the AA sequence of Rhesus macaque and Cynomolgus Complement Factor D are homologus.

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Ile 26 - Ala 253.

Conjugate: Unconjugated.

Molecular Weight: 26.5 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.5 kDa. The protein migrates as 25-27 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: 50 mM Tris, 150 mM NaCl, pH8.0.

Storage Conditions: -20℃.

Shipping Conditions: RT