Description
RGS3 Antibody | R31161 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-P
Buffer: N/A
Limitation: This RGS3 antibody is available for research use only.
Purity: Antigen affinity
Description: Regulator of G Protein Signaling 3 is a protein that in humans is encoded by the RGS3 gene. Chatterjee et al.(1997) studied RGS3, the largest member of the RGS family then identified. Mouse Pdz-Rgs3 can mediate signaling from the ephrin-B cytoplasmic tail. By radiation hybrid mapping, Chatterjee et al.(1997) assigned the gene to chromosome 9q31-q33. Lu et al.(2001) showed that Sdf1, a chemokine with a G protein-coupled receptor, and Bdnf are chemoattractants for cerebellar granule cells, and that Sdf1 chemoattraction is selectively inhibited by soluble ephrin-B receptor. This inhibition could be blocked by a truncated Pdz-Rgs3 protein lacking the RGS domain.
Immunogen: An amino acid sequence from the C-terminus of mouse Regulator of G Protein Signaling 3 (DSYTREHTKENLQSITR) was used as the immunogen for this RGS3 antibody (100% rat homology).
Storage: After reconstitution, the RGS3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
