RFC5 Antibody | F54778-0.4ML

RFC5 Antibody | F54778-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: FACS, WB

Buffer: N/A

Limitation: This RFC5 antibody is available for research use only.

Purity: Purified

Description: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. RFC5 is the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system.

Immunogen: A portion of amino acids 170-200 from the human protein was used as the immunogen for the RFC5 antibody.

Storage: Aliquot the RFC5 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.