RFC4 Polyclonal Antibody | E-AB-60987

RFC4 Polyclonal Antibody | E-AB-60987 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC, IF

Research Area: Cancer, Epigenetics and Nuclear Signaling

Background: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human RFC4 (NP_002907.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 33 kDa/39 kDa

Observed Molecular Weight: 40 kDa

Clonality: N/A