Description
Retinoblastoma Antibody / Rb1 | RQ5141 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: FCD-18
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This Rb1 antibody is available for research use only.
Purity: Affinity purified
Description: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [RefSeq]
Immunogen: A synthetic peptide specific to human Retinoblastoma / Rb was used as the immunogen for the Rb1 antibody.
Storage: Store the Rb1 antibody at -20 °C.
