Retinoblastoma Antibody / Rb1 | RQ5140

Retinoblastoma Antibody / Rb1 | RQ5140 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: BHC-18

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This Retinoblastoma antibody is available for research use only.

Purity: Affinity purified

Description: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [RefSeq]

Immunogen: A synthetic peptide specific to human Retinoblastoma / Rb was used as the immunogen for the Retinoblastoma antibody.

Storage: Store the Retinoblastoma antibody at -20 °C.