Retinal guanylyl cyclase 1 Antibody / GUCY2D | F54602-0.4ML

Retinal guanylyl cyclase 1 Antibody / GUCY2D | F54602-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Rat

Application: WB, IHC-P, FACS

Buffer: N/A

Limitation: This Retinal guanylyl cyclase 1 antibody is available for research use only.

Purity: Antigen affinity purified

Description: This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq].

Immunogen: A portion of amino acids 540-570 from the human protein was used as the immunogen for the Retinal guanylyl cyclase 1 antibody.

Storage: Aliquot the Retinal guanylyl cyclase 1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.