Description
RELA Antibody NF-kB p65 | R31513 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This RELA antibody is available for research use only.
Purity: Antigen affinity
Description: Transcription factor p65, also known as NFKB3 or NF-kB p65, is a protein that in humans is encoded by the RELA gene. It is mapped to 11q13.1. RELA is an essential transcription factor complex involved in all types of cellular processes, including cellular metabolism, chemotaxis, etc, and it may play a role in inflammatory conditions of the peripheral nervous system. Phosphorylation and acetylation of RELA are crucial post-translational modifications required for NFkB activation. It has also been shown to modulate immune responses, and activation of the protein is positively associated with multiple types of cancer. In addition, RELA antagonizes TNFR1-JNK proliferative signals in epidermis and plays a nonredundant role in restraining epidermal growth.
Immunogen: Human partial recombinant protein (AA 99-551) was used as the immunogen for this RELA antibody.
Storage: After reconstitution, the RELA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
