Description
Recombinant Transmembrane Protein 173 Monoclonal Antibody | E-AB-81615 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC-P
Research Area: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction
Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Lead Time: 7~10 days
Concentration: 300 μg/mL
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Immunogen: N/A
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Dilution: WB 1:500-1:1000 IHC 1:50-1:100
Conjugation: Unconjugated
Calculated Molecular Weight: 42kDa
Observed Molecular Weight: 40kDa
Clonality: Rabbit Monoclonal
