Recombinant Transmembrane Protein 173 Monoclonal Antibody | E-AB-81615

Recombinant Transmembrane Protein 173 Monoclonal Antibody | E-AB-81615 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC-P

Research Area: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction

Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Lead Time: 7~10 days

Concentration: 300 μg/mL

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Immunogen: N/A

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification: Affinity Purified

Dilution: WB 1:500-1:1000 IHC 1:50-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 42kDa

Observed Molecular Weight: 40kDa

Clonality: Rabbit Monoclonal