Recombinant SARS-CoV S-trimer Protein (C-6His)(Active) | PKSV030289

Recombinant SARS-CoV S-trimer Protein (C-6His)(Active) | PKSV030289 | Gentaur US, UK & Europe Disrtribition

Synonyms: SARS-CoV S-trimer Protein; SARS-CoV S protein; SARS-CoV Spike glycoprotein; SARS-CoV S glycoprotein

Active Protein: Active protein

Activity: Recombinant SARS-CoV S-trimer Protein is produced by our Mammalian expression system and the target gene encoding Ser14-Gln1190 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant SARS-CoV S-trimer Protein is produced by our Mammalian expression system and the target gene encoding Ser14-Gln1190 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: SARS

Expressed Host: Human Cells

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 134.9kDa 

Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4

Reconstitution: Not Applicable

Background: The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain

Research Area: Virus related Protein