Recombinant Rat UNC5B/UNC5H2 Protein (Fc Tag) | PKSR030375

Recombinant Rat UNC5B/UNC5H2 Protein (Fc Tag) | PKSR030375 | Gentaur US, UK & Europe Disrtribition

Synonyms: UNC5B

Active Protein: N/A

Activity: A DNA sequence encoding the rat UNC5B (NP_071543.1) (Met1-Asp373) was expressed with the Fc region of human IgG1 at the C-terminus.

Protein Construction: A DNA sequence encoding the rat UNC5B (NP_071543.1) (Met1-Asp373) was expressed with the Fc region of human IgG1 at the C-terminus.

Fusion Tag: C-Fc

Species: Rat

Expressed Host: HEK293 Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 85 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 65.7 kDa

Formulation: Lyophilized from sterile PBS, pH 7.4

Reconstitution: Please refer to the printed manual for detailed information.

Background: The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. In addition, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis.

Research Area: N/A