Recombinant Rat Lamin B1 Protein (His Tag) | PKSR040474

Recombinant Rat Lamin B1 Protein (His Tag) | PKSR040474 | Gentaur US, UK & Europe Disrtribition

Synonyms: ADLD;lamin B1;Lamin-B1;LMN;LMN2;LMNB;Lmnb1;LMNB1;MGC111419;OTTHUMP00000159218

Active Protein: N/A

Activity: A DNA sequence encoding the Rat Lamin B1 (P70615-1) (Arg387-Met587) was expressed with a polyhistidine tag at the N-terminus.

Protein Construction: A DNA sequence encoding the Rat Lamin B1 (P70615-1) (Arg387-Met587) was expressed with a polyhistidine tag at the N-terminus.

Fusion Tag: N-His

Species: Rat

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 22.1 kDa

Formulation: Lyophilized from sterile PBS, pH 7.4

Reconstitution: Please refer to the printed manual for detailed information.

Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).

Research Area: N/A