Description
Recombinant Rat CLM-9/TREM4 Protein (His Tag) | PKSR030178 | Gentaur US, UK & Europe Disrtribition
Synonyms: CD300LG
Active Protein: N/A
Activity: A DNA sequence encoding the rat CD300LG (XP_002724611.1) (Met1-Arg160) was expressed with a polyhistidine tag at the C-terminus.
Protein Construction: A DNA sequence encoding the rat CD300LG (XP_002724611.1) (Met1-Arg160) was expressed with a polyhistidine tag at the C-terminus.
Fusion Tag: C-His
Species: Rat
Expressed Host: HEK293 Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 17.5 kDa
Formulation: Lyophilized from sterile PBS, pH 7.4
Reconstitution: Please refer to the printed manual for detailed information.
Background: CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart, skeletal muscle, and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM.
Research Area: N/A
