Description
Recombinant Rat CD73/NT5E Protein (His Tag) | PKSR030462 | Gentaur US, UK & Europe Disrtribition
Synonyms: CD73; E5NT;Nucleotidase; NT5E;ecto-5'-nucleotidase;5'-Nucleotidase
Active Protein: N/A
Activity: Recombinant Rat 5'-Nucleotidase/CD73 is produced by our Mammalian expression system and the target gene encoding Trp29-Lys549 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Rat 5'-Nucleotidase/CD73 is produced by our Mammalian expression system and the target gene encoding Trp29-Lys549 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-His
Species: Rat
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 59 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 120mM NaCl, 4mM CaCl2, 20% Glycerol, pH 7.5.
Reconstitution: Not Applicable
Background: CD73, also known as Ecto-5'-nucleotidase, is an ectoenzyme that is attached to the cell membrane by a glycosyl phophatidylinositol anchor. The enzyme is expressed by most cell types. The 5 ’ -Nucleotidase activity of CD73 converts extracellular nucleoside-5 ’ -monophosphates to nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides.
Research Area: N/A
