Description
Recombinant Rat CD147/BSG/Basigin Protein (His Tag) | PKSR040468 | Gentaur US, UK & Europe Disrtribition
Synonyms: 5A11 antigen;5F7;BASI;Basigin (Ok blood group);Basigin;Blood brain barrier HT7 antigen;Bsg;CD 147;CD147;CD147 antigen;Collagenase stimulatory factor;EMMPRIN;Extracellular matrix metalloproteinase inducer;Leukocyte activation antigen M6;M 6;M6;M6 leukocyte activation antigen;Neurothelin;OK;OK blood group;OK blood group antigen;TCSF;Tumor cell derived collagenase stimulatory factor;Tumor cell-derived collagenase stimulatory factor
Active Protein: N/A
Activity: A DNA sequence encoding the Rat BSG (P26453-1) (Pro52-Thr324) was expressed with a polyhistidine tag at the N-terminus.
Protein Construction: A DNA sequence encoding the Rat BSG (P26453-1) (Pro52-Thr324) was expressed with a polyhistidine tag at the N-terminus.
Fusion Tag: N-His
Species: Rat
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 30.27 kDa
Formulation: Lyophilized from sterile PBS, pH 7.4
Reconstitution: Please refer to the printed manual for detailed information.
Background: BSG, also named as 5F7, Basigin, EMMPRIN, TCSF and CD147, plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS).CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA, inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix, plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.
Research Area: N/A
