Recombinant Rabbit IL1B protein(His tag) | PKSQ500012

Recombinant Rabbit IL1B protein(His tag) | PKSQ500012 | Gentaur US, UK & Europe Disrtribition

Synonyms: IL-1 beta;Lymphocyte proliferation-potentiating factor;IL-1B

Active Protein: N/A

Activity: A DNA sequence encoding theRabbit IL1B protein (P14628) (Ala117-Ser268) was expressed with a N-His.

Protein Construction: A DNA sequence encoding theRabbit IL1B protein (P14628) (Ala117-Ser268) was expressed with a N-His.

Fusion Tag: N-His

Species: Rabbit

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 80 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 17 kDa

Formulation: Lyophilized from sterile PBS, pH 7.5, 5% trehalose, 5% mannitol, 0.01% tween-80.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.

Research Area: N/A