Description
Recombinant NAT10 Monoclonal Antibody | E-AB-81427 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IF
Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction
Background: NAT-10 (N-acetyltransferase 10) is a nuclear protein that belongs to the UPF0202 family. It has a single N-acetyltransferase domain that likely functions as a histone acetyltransferase. NAT10 functions primarily to regulate the activity of telomerase. It is upregulated in response to DNA damage and is likely to take part in genotoxic resistance and DNA repair. NAT-10 has a high binding potential for the promoter region of TERT which stimulates the production of telomerase. These varieties of function imply that human telomerase complexes have multiple functions rather than specific duties.
Lead Time: 7~10 days
Concentration: 300 μg/mL
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Immunogen: N/A
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Dilution: WB 1:500-1:1000 IF 1:100-1:200
Conjugation: Unconjugated
Calculated Molecular Weight: 116kDa
Observed Molecular Weight: 116kDa
Clonality: Rabbit Monoclonal